IGF-1 LR3 1 mg

$105 — Growth Hormone Axis — purity 99%+

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is an 83-amino acid analog of human IGF-1 with an arginine substitution at position 3 and a 13-amino acid N-terminal extension. This modification dramatically reduces binding to IGF binding proteins (IGFBPs), resulting in enhanced bioavailability and a significantly longer half-life. Research demonstrates it activates the IGF-1 receptor, promoting cell proliferation, differentiation, and survival signaling via the PI3K/Akt and MAPK/ERK pathways.

Sequence: 83-amino acid modified IGF-1 (Arg³ substitution + N-terminal extension)

Storage: Store lyophilized material at -18°C or below in a controlled laboratory freezer. Reconstituted solution: hold at 2–8°C; validated stability window 2 weeks. Reconstitute using 0.1M acetic acid.

Analytical summary for lot T1B-7R99

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